In conclusion, in the present study, we found that eotaxin-1/CCL11 was up-regulated in sepsis-injured myocardium based on bioinformatic analysis and that circulating eotaxin-1/CCL11 was a biomarker for predicting severity and mortality of elderly patients with sepsis-induced myocardial injury based on observational clinical study. The gene discussed is CCL11; the disease is Sepsis.