Additionally, in the present study, a hypoxic experiment using a thyroid hormone-secreting HOTHC-sc-4D7 sub-clone derived from human anaplastic thyroid carcinoma (HOTHC) and a UD-PTC cell line derived from human thyroid papillary adenoma was conducted to corroborate the biochemical data from the autopsy materials. The gene discussed is TG; the disease is thyroid gland undifferentiated (anaplastic) carcinoma.