SOD1 and early-onset autosomal dominant Alzheimer disease: Importantly, oxidised wild‐type SOD1 recapitulates this toxic interaction,[165b] suggesting common pathogenic mechanisms and therapeutic targets between SOD1‐linked familial ALS and disorders exhibiting oxidised wild‐type SOD1, including sporadic ALS,[90b, 165b] Parkinson's disease[13, 91] and Alzheimer's disease.[91]