Contrastly, ILK inhibitor Cpd22 could increase the arrhythmia score after reperfusion (5.0 ± 1.2 vs 3.5 ± 1.5, P < 0.05); moreover, Cpd22 could abolish the effect of LPDT on arrhythmia score (3.6 ± 1.7 vs 1.7 ± 1.3, P < 0.05) (Fig. 1a). This evidence concerns the gene ILK and Arrhythmia.