The formation of the FAK-Src complex then triggers multiple downstream signaling pathways related to cell proliferation, invasion, migration, and death, which are critical for malignant tumor progression (Parsons, 2003; Cai et al., 2008; Hao et al., 2009; Provenzano and Keely, 2009; Lechertier and Hodivala-Dilke, 2012; Lee et al., 2015; Kleinschmidt and Schlaepfer, 2017). The gene discussed is PTK2; the disease is cancer.