We found that another tubulin depolymerization inhibitor Epothilone A, the ROCK 1/2 inhibitor GSK-269962A, the antimetabolite 5-Azacytidine, and the aminopeptidase inhibitor Tosedostat, visibly reduced cyst swelling at all or most concentrations tested (Fig. 4B and Supplementary Fig. 8). This evidence concerns the gene CPQ and cyst.