The color of ChREBP staining also changed from light red to dark red with colon cancer progression (Fig. 1Gc–f).To investigate how glycolysis and lipogenesis associate with colon cancer progression, the protein levels of glucose transporter, GLUT1 and GLUT2, involved in glycolysis30,31 were measured with immunohistochemistry and semi-quantification. The gene discussed is SLC2A2; the disease is malignant colon neoplasm.