Our findings in the present study revealed that miR-7 and miR-92b expression levels were markedly decreased in breast cancer surgery samples in contrast to the high expression of lncRNA XIST, RELA, CD44, slug, and ESA, suggesting a negative correlation between miR-7/miR-92b and the expression of BCSC stemness-related molecules in vivo. This evidence concerns the gene CD44 and breast carcinoma.