The most highly connected pathway in the CTP network was metabolic pathways (hsa01100, k = 29), followed by pathways in cancer (hsa05200, k = 21), metabolism of xenobiotics by cytochrome P450 (hsa00980, k = 15) and PI3K-Akt signaling pathway (hsa04151, k = 15). The gene discussed is AKT1; the disease is cancer.