Figure 4 shows the top 50 enriched pathways, among which the most significant were related to the actin cytoskeleton, focal adhesion and tight junctions, AMPK signaling, calcium signaling, PI3K-AKT signaling, pathways in cancer, arrhythmogenic right ventricular cardiomyopathy (ARVC), neuroactive ligand-receptor interactions, FoxO signaling, and p53 signaling pathways. This evidence concerns the gene TP53 and Arrhythmogenic right ventricular dysplasia.