Another study in 115 overweight/obese subjects with BED, 74 non-BED patients with obesity and 110 normal weight healthy controls investigated one of these FAAH polymorphisms, previously implicated in obesity and BED, reporting a lack of association [213] and, in a more recent article, these authors studied the association of this FAAH polymorphism and the CNR1 polymorphism in both AN and BN, in 134 patients with AN, 180 patients with BN and 148 normal weight healthy controls [214]. The gene discussed is CNR1; the disease is obesity due to melanocortin 4 receptor deficiency.