Among these factors, including the age, sex, primary tumor site, presence of ulceration, T category (thickness of primary tumor), N category (lymph node metastasis), and M category (distant metastasis), only the T category was significantly associated with BRAF status: thick, advanced melanomas (T3 or T4) were more likely to have BRAF V600E-mutated protein (p = 0.0015, Fisher’s exact test). Here, BRAF is linked to metastatic malignant neoplasm in the lymph nodes.