NPPB and coronary artery disorder: Elevated NT-proBNP levels not only precede the development of arterial hypertension, a major risk factor for CAD, but were inversely associated with myocardial perfusion reserve assessed by cardiac magnetic resonance before and after the administration of adenosine in 184 asymptomatic individuals, suggesting an association of NT-proBNP levels and microvascular dysfunction [16,17].