Expressed in most of the high-grade and stage PCs, IL-30 has been recently found to be expressed by the rare CD133+ PC stem-like cells (SLCs) that are located in the basal layer of prostatic intraepithelial neoplasia (PIN) in humans [81] (Figure 2a–c). The gene discussed is IL27; the disease is prostate intraepithelial neoplasia.