In fact, the fast-growing tumors that develop from IL-30-overexpressing PC–SLCs, show a prominent myeloid cell infiltrate that mainly consists of F4/80+ macrophages, CD11b+ myeloid cells, and Ly-6G+ granulocytes, which along with tumor progression is hampered by IL-30 knockdown [81];. This evidence concerns the gene ITGAM and neoplasm.