Interesting observations were also provided by the analysis of OPG concentration taking into account the degree of histological differentiation of cancer, which showed statistical significance between the degree of G1 and G3 differentiation in serous cancer, and in mucinous cancer between G1 and G3 as well as G2 and G3, which might be used in the creation of new therapeutic strategies. The gene discussed is TNFRSF11B; the disease is cancer.