Studies conducted so far have shown that ovarian tumours are accompanied by changes in the concentration of markers monitoring the process of apoptosis in the following ligand/receptor systems: TNF/sTNF-R, sCD30/sCD30L, sCD40/sCD40L, and soluble tumour necrosis factor ligand inducing apoptosis (sTRAIL)/sTRAIL-R1 and R2. Here, TNF is linked to ovarian neoplasm.