NFKB1 and cancer: The molecular signaling pathways regulated by green tea catechols resulting in their pro-apoptotic and anti-proliferative effects include, among others, inhibition of nuclear factor-κB (NF-κB) which is the crucial oxidative stress-sensitive transcription factor [14,35] NF-κB plays a critical role in the regulation of a variety of genes important in cellular responses, including inflammation, proliferation and cancer cell death.