IL6 and Cachexia: The pro‐inflammatory cytokine IL‐6 is found in high levels in cachectic patients and is correlated with weight loss.28, 61, 75 IL‐6 was associated with cachexia in rodent models58, 61, 76 and is thought to induce the activation of inflammatory and catabolic pathways, resulting in the suppression of protein synthesis in muscle cells by Janus kinase (JAK) signalling.58, 61, 75, 76, 77 Inflammation by IL‐6 also induces lipolysis and the browning of the white adipocytes, apparently through up‐regulation of UCP1.3, 78, 79