CD27 and autoimmune hepatitis: It is generally believed that abnormal selection of high‐affinity autoantibody‐producing plasma cells in germinal centre (GC) plays a central role of AIH.8 We previously characterized hyperactive B‐cell immunity in AIH patients and found that original B cells can differentiate into CD27+ memory and CD138+ plasma cells that produce autoantibodies, such as anti‐nuclear antibodies.4 This differentiation process of B cells requires the help of TFH cells,4, 9, 10, 11 which is one of the important regulators of humoural immune responses.