Thus, we derived the following prediction equation of serum markers combined detection for LLNM in MTC patients by logistic regression analysis (enter method) (as shown in Table 3): Logistic (P) = −3.5390.002 × Ctn + 0.001 × CEA + 0.151 × NSE. This evidence concerns the gene ENO2 and medullary thyroid gland carcinoma.