MTOR and epilepsy: In local gene expression on synapses, the ERK pathway is involved with the synthesis of N‐methyl‐D‐aspartic acid (NMDA) receptor that may contribute toward synaptic excitability and the expression level of mTOR maintained the synthesis of GABAergic and glutamatergic signaling, both of which may contribute toward epilepsy formation.35, 36 The seizure outcomes of the mice with GR treatment were accompanied by a reduction of the p‐mTOR level.