ALDH1A1 and metabolic dysfunction-associated steatotic liver disease: However, a systematic transcriptome analysis revealed that the expression of alcohol-metabolizing enzymes, including ADH, ALDH (ALDH1A1, ALDH1B1, ALDH3B1, ALDH4A1, ALDH7A1, and ALDH9A1), CYP2E1, and CAT, was higher in NAFLD livers (72 NAFLD patients and 7 controls) 72.