TOMM5 and central nervous system cancer: Within the glioma dataset, two of the functionally enigmatic genes with a strong association with phenotype (MRS2 - mitochondrial and TOMM5, which has a primate-specific isoform) were in a module (“blue”) with the top three annotations as relatively high-level terms (single-organism intracellular transport, intracellular transport, and cellular catabolic process).