Of these, genes hypothesized to have a tumor-suppressor function included LINC00886, MAN2C1, SNUPN, and STC1, while YBEY, SEMA4A, and MUTYH may have an oncogenic role in breast carcinogenesis based on their associations with breast cancer risk (Supplementary Table 7). The gene discussed is SEMA4A; the disease is breast cancer.