FPR2, also known as the lipoxin A4 receptor (LXA4R, ALX), plays important roles in chemotaxis, cell proliferation, wound healing, migration, and vessel growth, and is involved in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis, colitis, Alzheimer’s disease, systemic amyloidosis and atherosclerosis2,3. Here, FPR2 is linked to Alzheimer disease.