In contrast to the tumor EC findings, EC from lungs and livers collected from the same LLC-allografted Cds2 vMO-treated mice that the tumors were isolated from show no reduction in levels of PIP2, p-AKT, or p-ERK1/2 (Fig. 4j-l, n; Supplementary Fig. 14B–E). Here, CDS2 is linked to neoplasm.