We previously revealed that a novel probiotics mixture can suppress hepatocellular carcinoma growth in mice by reducing the frequency of Th17 cells, the main producers of the IL-17 cytokine, in the intestine and their subsequent recruitment to the tumor bed [9], whereas Akkermansia muciniphila was recently identified as being associated with increased intratumoral immune infiltrates into the tumor bed in response to PD-1 blockade therapy [13]. This evidence concerns the gene IL17A and neoplasm.