In the study of a diabetic myocardial infarction model, the regulatory role of thioredoxin-interacting protein on the Wnt/β-catenin signaling pathway was mainly achieved by altering the levels of reactive oxygen species, which was accompanied by changes in the expression of its downstream proteins cyclin D1 and C-myc [41]. Here, CCND1 is linked to myocardial infarction.