NCR3LG1 and cancer: Therefore, considering that cervical microbiota changes through progressive intraepithelial lesions advancing toward cancer, which is characterized by the presence of gram-negative bacteria, including Fusobacterium spp [31], we cannot discard the possibility that microbial diversity associated with either squamous cervical carcinoma or cervical adenocarcinoma might be able to activate different inflammatory pathways influencing consequently the production of soluble or membrane forms of B7-H6.