A comprehensive meta-analysis of 58 clinical trials and 3974 subjects has recently showed that oat beta-glucan significantly affects the serum concentrations of low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C) and apolipoprotein-B (apo-B), concluding that the inclusion of oat-containing foods in the diet may be a valid strategy to prevent the onset of cardiovascular disease [2]. This evidence concerns the gene APOB and cardiovascular disorder.