In addition to p53 and RREB1, miR-145 is regulated by other transcription factors, including CCAAT/enhancer-binding protein beta (C/EBPβ), beta-catenin/T cell factor 4 (TCF4), and forkhead transcription factors FOXO1 and FOXO3 in human cancers [36,37]. The gene discussed is TP53; the disease is cancer.