These metabolites are involved in mitochondrial function and oxidative stress, two cellular processes that are altered in SCA7 [13,15,16], and other neurodegenerative disorders, including Alzheimer’s Disease (AD), Parkinson Disease (PD), and Huntington Disease (HD) [34,35,36]. The gene discussed is ATXN7; the disease is early-onset autosomal dominant Alzheimer disease.