Our observations might provide an explanation for a higher IL2RA (CD25) expression among FLT3/ITD myeloblasts, as well as its correlation with FLT3/ITD allelic burden (Abd El‐Ghaffar et al, 2016), and corroborated with recent findings of CD25 as one of the leukemia‐associated immunophenotypes (LAIP) specific for FLT3/ITD AML (Angelini et al, 2015). This evidence concerns the gene IL2RA and leukemia.