Ma et al. (2019) reported that miR-199a-3p is poorly expressed in HCC cells and HEIH silence suppressed the activation of mTOR signaling via upregulating miR-199a-3p (Ma et al., 2019). Ren et al. (2016) reported that miR-199a-3p could inhibit the proliferation of HCC cells by targeted down-regulating YAP1 expression (Ren et al., 2016). Here, HEIH is linked to hepatocellular carcinoma.