Previously, we showed that BM-MSCs from SLE patients exhibited abnormalities in modulating immune cells (7), and allogenic MSCs transplantation up-regulated Treg cells and down-regulated Th17 cells through the regulation of transforming growth factor β1 (TGF-β1) and prostaglandin E2 (PGE2) in lupus patients (8). The gene discussed is TGFB1; the disease is systemic lupus erythematosus.