The role of PCT in detecting sepsis in immunocompromised patients, however, remains controversial as studies have shown conflicting results.32-35 On the other hand, PCT has demonstrated an acceptable accuracy for the diagnosis of bacterial infections in septic patients with liver cirrhosis compared to patients with normal liver function.36 These results contrast with those of Tang et al.37 who described a low diagnostic performance of PCT in differentiating sepsis from non-infectious SIRS in critically ill adults. This evidence concerns the gene CALCA and cirrhosis of liver.