VEGFC and cancer: VEGFC is one of the key factors promoting malignant cell spread, as demonstrated both in mouse tumor models (Mandriota et al, 2001; Skobe et al, 2001; Ma et al, 2018) and during human cancer progression (Thiele & Sleeman, 2006; Rinderknecht & Detmar, 2008; Chen et al, 2012; Jiang et al, 2014).