IRF4 and atrial fibrillation: We observed exon duplications in MYC (AF range 0.13–0.88), BCL11B (AF range 0.12–.22), CEBPA (AF range 0.10–0.79), and ZCCHC7 (AF range 0.11–0.83), while exon deletions were noted in IRF4 (AF range 0.12–0.55), IKZF1 (AF range 0.40–0.44) and SETD2 (AF range 0.11–0.21) (Fig. 4b and Additional file 7: Table S3).