INS and type 2 diabetes mellitus: The bivariate analyses revealed significant associations between incident type 2 diabetes and education level, anti-hyperlipidemic medication use, age, physical activity, systolic blood pressure, BMI, waist circumference, HDL cholesterol, triglyceride, HOMA-IR, fasting insulin, fasting glucose, HbA1c, plasma leptin, and plasma adiponectin (Table 1).