Representative dot plots of the expression of CD38, HLA-DR, and Ki67 on total cytokine CD4+ T-cells are shown in Figure 5A. All individuals tested had a positive CD4+T-cell response to Mtb-Lysate while 9/12 (75%) HIV+TB and 8/9 (89%) LTBI individuals had responses to ESAT-6/CFP10. This evidence concerns the gene MKI67 and tuberculosis.