CD4 and tuberculosis: We observed that a high ratio was associated with active TB on ESAT-6/CFP-10 (p = 0.01 for HIV−TB vs. LTBI and p = 0.05 for HIV+TB vs. LTBI, Figure 8A), but not the Mtb-Lysate stimulated CD4+ T-cells (p = 0.10; results not shown).