Regarding the prognostic role of miR-221-3p/miR-222-3p expression in the TKI response of ccRCC patients and the downregulation of miR-221-3p/miR-222-3p in PCa tissue, we wanted to find out whether miR-221-3p also regulated VEGFR2 in PCa cells. The gene discussed is KDR; the disease is nonpapillary renal cell carcinoma.