In a genetically engineered mouse model of inducible CRC, Villin-CreERT2, Apcf/f, Trp53f/f, and tetO-LSL-KrasG12D [29], the expression levels of CPT1, FABP4, and SCD1 (Figure S4B) were significantly upregulated whereas the expression level of Nudt7 was dramatically decreased when KrasG12D was turned on (+DOX; KrasON; 0.51-fold of KrasOFF) (Figure 2C). The gene discussed is SCD; the disease is colorectal carcinoma.