The increased levels of peroxisomal coenzyme A diphosphatase 7 (NUDT7) and acyl-CoA oxidase 1 (ACOX1) expressed in the epithelial cells and colonic glands in Nudt7+/+_AOM/DSS colon were significantly decreased in Nudt7−/−_AOM/DSS colon (Figure 4C). Here, NUDT7 is linked to infectious otitis media.