NOS2 and retinal degeneration: By treating cells or organotypic explant with CoCl2, hypoxia can be induced ex vivo and the pathological mechanism simulated.3, 34, 39 CoCl2, similar to hypoxia, prevents the degradation of the α‐subunit of hypoxia‐inducible factor and thus mediates its stabilization.40 With our CoCl2 induced retinal degeneration model, we already proved the neuroprotective effect of hypothermia.4 Here, we specifically examined the influence of the inhibition of iNOS on the course of degeneration.