CASP4 and lepromatous leprosy: NLRP3 inflammasome’s immunohistochemical strong expression score is ahallmark of the Lepromatous Leprosy - The immunohistochemicalexpression of NLRP3, caspase-1, caspases-4/5, IL-1β, IL-6, and IL-18 between thegroups presented statistically significant differences in the scores (Table I).