SREBF1 and metabolic syndrome: SREBP-1C is acrucial transcription factor, which binds to the endoplasmic reticulum to regulatetriglyceride and fatty acid synthesis (26).Moreover, SREBP-1C is involved in de novo fatty acid synthesis viaregulating the expression of ACC (27).Previous research indicated that decreasing the expression of SREBP-1C results in adecline of the incidence of dyslipidemia and simultaneously suppresses ACCexpression in C57BL/6J mice (28).