Besides improving microbiological detection of TB, e.g. by Xpert MTB/RIF Ultra [51], lateral flow urine lipoarabinomannan assay (LF-LAM) [52] or adenosine deaminase [53, 54], the clinical evaluation might benefit from integration of an additional standardized testing, such as e.g. Focused Assessment with Sonography for HIV and Tuberculosis (FASH) [25, 55]. Here, ADA is linked to tuberculosis.