DNM2 and centronuclear myopathy: To assess whether the lasting myopathy is related to an increase in centronucleated fibres, a cardinal feature in CNM patients with a distinct set of DNM2 mutations, we quantified the number of fibres with central nuclei in soleus muscles of 1-year-old Dnm2 wt/K562E and control mice but detected no significant changes (Supplementary Material, Fig. S4E).