DNM2 and myopathy: In accordance with a myopathy and reduced fibre size, the weight of soleus muscles (including the calcaneal tendon, used for handling the tissue) was significantly lower in Dnm2 wt/K562E male and females mice compared to respective sex controls at 1 year of age and also already significantly reduced in 2-month-old Dnm2 wt/K562E males (Supplementary Material, Fig. S4D).