NR3C2 and Hypertension: Whilst it is true that MR activation contributes to renal damage in the context of hypertension, a blood pressure‐independent effect has been demonstrated in various models of kidney injury including subtotal nephrectomy (Ibrahim & Hostetter, 1998), ischaemia\reperfusion injury (Barrera‐Chimal et al., 2015; Mejía‐Villet et al., 2007; Ramírez et al., 2009), diabetic nephropathy (Bamberg et al., 2018), glomerulonephritis (Asai et al., 2005) and calcineurin inhibitor nephrotoxicity (Feria et al., 2003).