EGFR and lung adenocarcinoma: The effect of EGFR mutation status on tumor malignancy and prognosis is interfered by many factors, such as tumor stage and treatment method, etc. Our next study is to further investigate if EGFR mutation status and DNA aneuploidy are independent factors affecting the prognosis and survival of patients with lung adenocarcinomas by supplementing and refining follow-up data, and to design basic experiments to test whether different levels of DNA aneuploidy can change the proliferation, invasion and metastasis ability of lung adenocarcinoma cells.