Using UALCAN database 9, we analyzed the expression of YWHAZ in tumor tissues and adjacent tissues from nine types of high-morbidity cancers and observed that YWHAZ was significantly increased in breast carcinoma (BRCA), colon adenocarcinoma (COAD), esophagus carcinoma (ESCA), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), lung squamous carcinoma (LUSC) and stomach adenocarcinoma (STAD) (p < 0.0001). This evidence concerns the gene YWHAZ and colon adenocarcinoma.