Currently researches on CRC-related biomarkers continue to grow 6, for example, related studies have shown that vascular endothelial growth factor (VEGF) is expressed in about 50% of CRC, which is very rarely expressed in normal colon mucosa and adenoma, and VEGF-1 can effectively predict the prognosis of CRC patients 7. This evidence concerns the gene VEGFA and colorectal carcinoma.